tudying the interactions of drugs and hydrophobic model membranes using ontact angle goniometry
نویسندگان
چکیده
This study demonstrates amethodwhere contact angle goniometry combinedwith surface tensionmeasurements is used to assess the interactions of drugswith the hydrophobic core of a biologicalmembrane. To this end, self-assembledmonolayers (SAMs) of two alkanethiol and one thiolipid on Au(111) surfaces are used asmodelmembranes and their interactionwith six -blockers is studied. TheGibbs equation and vailable online 21 January 2009
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